KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCG1
All Species:
18.18
Human Site:
T576
Identified Species:
36.36
UniProt:
P19174
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19174
NP_002651.2
1290
148532
T576
L
T
E
Y
C
I
E
T
G
A
P
D
G
S
F
Chimpanzee
Pan troglodytes
XP_514650
1630
185027
T916
L
T
E
Y
C
I
E
T
G
A
P
D
G
S
F
Rhesus Macaque
Macaca mulatta
XP_001087295
1291
148567
T576
L
T
E
Y
C
I
E
T
G
A
P
D
G
S
F
Dog
Lupus familis
XP_542998
1249
143812
V545
A
P
D
G
S
F
L
V
R
E
S
E
T
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q62077
1302
149650
T576
L
T
E
Y
C
I
E
T
G
A
P
D
G
S
F
Rat
Rattus norvegicus
P10686
1290
148530
T576
L
T
E
Y
C
I
E
T
G
A
P
D
G
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
Q113
A
N
T
P
E
E
A
Q
C
W
I
Q
G
L
E
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
R139
H
T
Q
E
E
A
E
R
W
V
R
G
I
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
P450
L
P
D
H
P
L
D
P
G
L
P
L
P
P
P
Honey Bee
Apis mellifera
XP_624101
1134
132613
E489
G
K
L
A
R
G
R
E
E
A
E
E
L
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784329
940
107748
E295
P
L
R
S
R
D
L
E
V
R
L
T
E
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79
99.5
93.2
N.A.
95.3
96.9
N.A.
N.A.
21.4
21.7
21.8
N.A.
21.4
45.1
N.A.
35.1
Protein Similarity:
100
79
99.7
94.5
N.A.
96.7
98.2
N.A.
N.A.
32.4
37.3
36.3
N.A.
40
62
N.A.
50
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
0
6.6
13.3
N.A.
20
6.6
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
0
6.6
20
N.A.
46.6
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
0
9
9
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
42
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
0
9
9
0
0
0
0
42
0
0
0
% D
% Glu:
0
0
42
9
17
9
50
17
9
9
9
17
9
0
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
42
% F
% Gly:
9
0
0
9
0
9
0
0
50
0
0
9
50
0
0
% G
% His:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
42
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
50
9
9
0
0
9
17
0
0
9
9
9
9
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
17
0
9
9
0
0
9
0
0
50
0
9
17
9
% P
% Gln:
0
0
9
0
0
0
0
9
0
0
0
9
0
0
0
% Q
% Arg:
0
0
9
0
17
0
9
9
9
9
9
0
0
9
9
% R
% Ser:
0
0
0
9
9
0
0
0
0
0
9
0
0
42
0
% S
% Thr:
0
50
9
0
0
0
0
42
0
0
0
9
9
0
9
% T
% Val:
0
0
0
0
0
0
0
9
9
9
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% W
% Tyr:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _